Fecal Viral Load and Norovirus-associated Gastroenteritis

نویسندگان

  • Martin C.W. Chan
  • Joseph J.Y. Sung
  • Rebecca K.Y. Lam
  • Paul K.S. Chan
  • Nelson L.S. Lee
  • Raymond W.M. Lai
  • Wai K. Leung
چکیده

We report the median cDNA viral load of norovirus genogroup II is >100-fold higher than that of genogroup I in the fecal specimens of patients with norovirus-associated gastroenteritis. We speculate that increased cDNA viral load accounts for the higher transmissibility of genogroup II strains through the fecal-oral route.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Fecal Viral Concentration and Diarrhea in Norovirus Gastroenteritis

Fecal viral concentrations of 40 patients infected with norovirus genogroup GII.4 correlated with diarrhea duration and frequency of vomiting. Higher viral concentration and older age were independently associated with prolonged diarrhea (> or =4 days). These findings provide information on the pathogenesis and transmission of norovirus infections.

متن کامل

Norovirus infections in symptomatic and asymptomatic food handlers in Japan.

Noroviruses are the leading cause of outbreaks of gastroenteritis in the world. At present, norovirus genogroup II, genotype 4 (GII/4), strains are the most prevalent in many countries. In this study we investigated 55 outbreaks and 35 sporadic cases of norovirus-associated gastroenteritis in food handlers in food-catering settings between 10 November 2005 and 9 December 2006 in Japan. Stool sp...

متن کامل

Eight different viral agents in childhood acute gastroenteritis.

Viral gastroenteritis is the most frequent cause of acute gastroenteritis (AGE) of childhood. The aim of this study was to determine the prevalence of viral agents including astrovirus, rotavirus, adenovirus, enterovirus, norovirus, parechovirus, Aichivirus and sapovirus in children with AGE in a pediatric Turkish population. Fecal specimens of 240 children with AGE were investigated by polymer...

متن کامل

Spinal Expanding Lesions Extradural Spinal Arachnoid Cysts

The clinical features of benign convulsions with mild gastroenteritis (CwG) were studied retrospectively in 62 patients hospitalized (Jan 2000-March 2006) at St Mary's Hospital, Kurume City, Japan. Viral infections confirmed in 71% of fecal specimens were rotavirus in 30 patients, norovirus in 9, sapovirus in 2, adenovirus in 2, and coxsackievirus A4 in 1. Age of patients with norovirus (16.7 +...

متن کامل

Unrecognized norovirus infections in health care institutions and their clinical impact.

Noroviruses (NoVs) have emerged as the leading cause of acute viral gastroenteritis (GE) in humans. Although diagnostic facilities have greatly improved, significant underdiagnosis of NoV in hospitals may still occur, thereby increasing clinical burden and nosocomial spread. We evaluated the underdiagnosis of sporadic NoV infections in a tertiary care hospital and estimated its clinical impact....

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 12  شماره 

صفحات  -

تاریخ انتشار 2006